C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/272
C07D 471/14 (2006.01)
Patent
CA 1071628
ABSTRACT OF THE DISCLOSURE The invention relates to new indolo-quinolizidine derivatives of the general formula (I) or salts or optically active isomers thereof, (I) Image wherein R stands for an alkyl group, and pharmaceutical compositions containing the same, as well as to a process for the preparation thereof. The new compounds according to the invention possess vasodilatating and hypotensive effects and can be used in the therapy as medicines. The new compounds according to the invention are completely devoid of harmful side-effects The compounds of the general formula (I), or their salts or optically active isomers, respectively, are prepared according to the invention as follows: a compound of the general formula (IV), (IV) Image wherein R stands for an alkyl group, or a salt thereof is
240411
Kalaus Gyorgy
Karpati Egon
Szabo Lajos
Szantay Csaba
Szporny Laszlo
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