Dioxane hexenoic acids

Details Dioxane hexenoic acids Dioxane hexenoic acids

C - Chemistry, Metallurgy

07

D

167/242, 167/244

C07D 407/04 (2006.01) A61K 31/38 (2006.01) C07D 409/04 (2006.01)

Patent

CA 1277329

ABSTRACT OF THE DISCLOSURE The invention concerns novel 1,3-dioxane hexenoic acids and related carboxylic acid esters and alkanesulphonamides of the formula I Image I in which X is oxy or thio, R1 is hydrogen, halogeno, trifluoro- methyl, cyano or nitro and R2 is hydrogen, together with their pharmaceutically acceptable salts. The invention also concerns processes for the production of the novel compounds and pharmaceutical compositions containing the compounds for use in the treatment of various diseases in which thromboxane A2 (TXA2) is implicated.

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