Ethanone oximes

Details Ethanone oximes Ethanone oximes

C - Chemistry, Metallurgy

07

D

260/202, 167/211

C07D 295/13 (2006.01) C07D 279/30 (2006.01) C07D 295/125 (2006.01) C07D 307/91 (2006.01) C07D 333/76 (2006.01) C07D 339/08 (2006.01) C07D 409/06 (2006.01) C07D 417/06 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1338711

Ethanone oximes represented by the following general formula: Image (I) wherein R1 represents a cycloalkyl group, aryl group, aralkyl group, aryloxy group, aralkyloxy group, arylthio group or aryl sulfonyl group, those groups being optionally substituted with a substituent selected from an alkyl group having 1 to 3 carbon atoms, an alkoxy group having 1 to 3 carbon atoms and a halogen atom, piperidino group, piperazino group, 4-alkyl substituted piparazino group, imidazolyl group, 4-alkyl substituted imidazolyl group or substituted amino group, R2 represents a hydrogen atom or an alkoxy group having 1 to 3 carbon atoms, and R3 represents a piperidino group, piperazino group or 4-alkyl substituted piperazino group, or R1 and R2 together with a phenyl group to which they are attached may form a phenothiazin-2-yl group, N- acetyl-phenothiazin-2-yl group, thianthren-2-yl group, dibenzothiophen-3-yl group, dibenzofuran-3-yl group or a group of the formula: Image wherein R4 represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, or a pharmaceutically acceptable acid addition salts thereof are disclosed. They are a potent antiulcer agent.

576488

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