Dilution and mixing cartridge

G - Physics – 01 – N

Patent

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G01N 1/28 (2006.01) G01N 1/38 (2006.01) G01N 33/04 (2006.01)

Patent

CA 1323999

ABSTRACT OF THE DISCLOSURE A dilution and mixing cartridge for automatically measuring and diluting a liquid sample with a liquid diluent. There is a housing able to receive a sample and a flow directing chamber formed as an internal chamber in the housing. A sample can be delivered from the flow directing chamber. Diluent can be received and delivered to the flow directing chamber. A receiving chamber is formed as a vented internal chamber in the housing. A measuring chamber is also present in the housing and has a volume smaller than the volume of the receiving chamber. The measuring chamber connects the flow directing chamber to the receiving chamber. The measuring chamber is capable of delivering sample and diluent from the flow directing chamber to the receiving chamber solely by capillary and gravitational forces. A stop flow junction is located at the end of the measuring chamber. The stop flow junction provides sufficient back pressure resulting from contact between the sample and the wall of the housing at the stop flow junction to prevent sample from flowing through the stop flow junction in the absence of diluent but allowing flow through the junction when diluent enters the flow directing chamber. The flow directing chamber can be emptied after sample has entered it and has filled the measuring chamber. The emptying is carried out by capillary and gravitational forces. Thus diluent flows through the flow directing chamber and expels sample from the measuring chamber into the receiving chamber. This causes a fixed ratio of sample to diluent to be delivered to the receiving chamber.

613158

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