Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics

Details Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics

C - Chemistry, Metallurgy

07

F

260/111, 260/488

C07F 7/10 (2006.01) C07D 409/12 (2006.01) C07D 499/88 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1264736

PATENT DPC-6949A 72222-3 PROCESS FOR 2-(1-OXO-3- THIOLANYL)-2-PENEM ANTISIOTICS Abstract Process and intermediates for the conversion of 3R,4R-4-acetoxy-3-[1R-1-(silyloxy)ethyl]-2-azetidinones to antibacterial 5R,6S-6-(1R-1-hydroxyethyl)-2-(1-oxo- 3-thiolanylthio)-2-penem-3-carboxylic acids, and the pharmaceutically-acceptable salts and pivaloyloxymethyl esters thereof.

520487

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