Fused aromatic oxazepinones and sulfur analogs thereof in a...

C - Chemistry – Metallurgy – 07 – D

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C07D 267/14 (2006.01) C07D 281/10 (2006.01) C07D 498/04 (2006.01)

Patent

CA 1234809

419A-CIP FUSED AROMATIC OXAZEPINONES AND SULFUR ANALOGS THEREOF ABSTRACT OF THE INVENTION Aromatic-2,3-dihydro-1,4-oxazepin-5(4H)-ones and sulfur analogs thereof having the formula Image whexein B and E are oxygen and/or sulfur, n is 1, 2 or 3, Z is -NR1R2, 1H-pyrazol-l-yl ox 1H-imidazol-l-yl and R is loweralkyl, cycloalkyl or phenylloweralkyl having antihistaminic application, a process for the preparation thereof, and intermediates therefor are disclosed.

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