Process for preparing novel n-substituted derivatives of...

C - Chemistry – Metallurgy – 07 – D

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167/223, 167/274

C07D 295/10 (2006.01) A61K 31/135 (2006.01) C07D 295/084 (2006.01)

Patent

CA 1243319

- 1 - "1-(4'-ALKYLTHIOPHENYL)-2-AMINO-1,3-PROPANEDIOL N-SUBSTITUTED DERIVATIVES". ************** ABSTRACT N-substituted derivatives of 1-(4'-alkylthiophenyl)-2-amino- -1,3-propanediol, their salts with pharmaceutically acceptable organic and inorganic acids, processes for preparing them, phar- maceutical compositions containing them and intermediates useful in the preparation thereof. The novel derivatives according to this invention are endowed with calcium antagonist activity and are useful as antiarrhyth- mic and vasodilating agents.

460079

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