Process for the culture of hepatocytes and hepatocyte...

Details Process for the culture of hepatocytes and hepatocyte... Process for the culture of hepatocytes and hepatocyte...

C - Chemistry, Metallurgy

12

N

195/46

C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12N 13/00 (2006.01)

Patent

CA 1281676

BREVET D'INVENTION PROCEDE DE CULTURE DES HEPATOCYTES ET CO-CULTURES D'HE- PATOCYTES ET DE CELLULES EPITHELIALES DE FOIE TRAITEES. IRE-CELLTARG S.A. Inventeurs :-PIRSON Philippe Jean -CLAIKENS Vinciane Michèle -SCHNEIDER Yves-Jacques, Emile AREGE DESCRIPTIF La présente invention concerne un procédé de culture des hépatocytes, permettant de maintenir l'inté- gralité de leurs fonctions spécifiques, caractérisé en ce que lesdits hépatocytes sont mis en co-culture avec des cellules de foie de type épithélial dont les capacités de division ont été définitivement inhibées par un traite- ment approprié.

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