Process for producing acyloxy aromatic carboxylic acid

C - Chemistry – Metallurgy – 07 – C

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C07C 65/05 (2006.01) C07C 45/46 (2006.01) C07C 45/54 (2006.01) C07C 49/825 (2006.01) C07C 51/09 (2006.01) C07C 65/03 (2006.01) C07C 69/035 (2006.01)

Patent

CA 1255327

ABSTRACT OF THE DISCLOSURE Acyloxy aromatic carboxylic acids, e.g., 4-acetoxybenzoic acid, are prepared by oxidizing with oxygen an acyloxy aromatic ketone, e.g., 4-acetoxyacetophenone in the presence of transition metal ions as catalyst and a co-reductant. The acyloxy aromatic ketone may be prepared by acylating a hydroxy aromatic ketone, e.g., 4-hydroxyacetophenone, which has the effect of "masking" the hydroxyl group of the ketone in a manner necessary to effect the subsequent transition-metal catalyzed oxidation of the ketone to the acyloxy aromatic carboxyic acid.

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