Tissue protein pp in21 xx, a process for obtaining it and...

C - Chemistry – Metallurgy – 07 – K

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167/104, 530/9,

C07K 9/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1243014

Abstract of the disclosure: The protein PP21 which has the following characteristics: a) an electrophoretic mobility in the region of that of .beta.1-globulins, b) an isoelectric point of 4.6 ? 0.3; c) a sedimentation coefficient s20,w of 3.2 ? 0.2 S; d) a molecular weight determined in an ultracentrifuge of 52,900 ? 6,200; e) an extinction coefficient E??m(280 nm) of 10.5 ? 1.0; and f) a carbohydrate fraction of 19.2 ? 5.2 g/100 g (man- nose 1.8 ? 0.4, galactose 4.3 ? 1.0, fucose 1.3 + 0.3, N-acetylglucosamine 6.5 ? 2.0 and N-acetylneura- minic acid 5.3 ? 1.5, each g/100 g), and a specified amino acid composition, a process for obtaining it and its use are described.

477146

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