Substituted benzenesulfonic esters, a process for their...

Details Substituted benzenesulfonic esters, a process for their... Substituted benzenesulfonic esters, a process for their...

C - Chemistry, Metallurgy

07

C

260/464.5

C07C 335/28 (2006.01) C07C 309/73 (2006.01) C07C 309/75 (2006.01) C07C 309/76 (2006.01) C07C 317/14 (2006.01) C07C 323/66 (2006.01)

Patent

CA 1214182

ABSTRACT OF THE DISCLOSURE New benzenesulfonic esters of the formula I Image I in which R1 denotes straight-chain or branched alkyl having 1 - 4 carbon atoms, n denotes 1, 2, or 3 and the individual substituents R2, independ- ently of one another, denote hydrogen, fluor- ine, chlorine, bromine, iodine, cyano, nitro, trifluoromethyl, 1,1,2,2-tetrafluoroethoxy, straight-chain or branched alkyl having 1 - 12 carbon atoms, cyclo-alkyl having 3 - 8 carbon atoms, alkoxy, alkyl-thio, alkylsulfinyl or alkylsulfonyl, each having 1 - 6 carbon atoms in the alkyl radical, acetyl, acetamino, or phenyl, phenoxy, phenylthio, phenylsulfinyl or phenylsulfonyl, each of which is optionally substituted once or twice by halogen, R3 denotes hydrogen or -CO-R4, in which R4 denotes alkyl or alkoxyalkyl which are optionally sub- stituted by halogen, and each of which have 1 - 6 carbon atoms in an alkyl moiety, or phenyl which is optionally substituted by halogen, methyl or methoxy, X denotes -SO2-O- or -O-SO2 and Z denotes =S; =N-COOR1 or =NH and a process for their preparation are described. The new compounds are active against helminths and can thus be used as agents to counter worms in humans and animals.

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