Benzhydrylsulfinylethylamine derivatives

Details Benzhydrylsulfinylethylamine derivatives Benzhydrylsulfinylethylamine derivatives

C - Chemistry, Metallurgy

07

C

260/602.2

C07C 317/28 (2006.01) A61K 31/13 (2006.01) A61K 31/135 (2006.01)

Patent

CA 1215393

-8- ABSTRACT The present invention relates as new industrial products to the N-[2-(benzhydrylsulfinyl)-ethyl]-amines of formula: (C6H5)2 CH - SO - CH2CH2 - NHR (I) (wherein R is H or C1-C4-alkyl) and to the acid addition salts thereof. These new products are useful in therapeutics, particularly as anti- depressants of the CNS. They may be prepared by condensation of diphenylmethanethiol with a 2-bromoethylamine of formula BrCH2CH2NHR (wherein R is defined as indicated hereinabove) then oxidization by means of H2O2.

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