Antibiotics, benanomicins a and b and dexylosylbenanomicin...

C - Chemistry – Metallurgy – 07 – H

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195/107, 167/185

C07H 15/252 (2006.01) A61K 31/70 (2006.01) C07H 15/24 (2006.01) C12P 19/56 (2006.01)

Patent

CA 1339016

Two new antibiotics which are now nominated as benanomicin A and benanomicin B, respectively, are fermentatively produced by the cultivation of a new microorganism, designated as MH193-16F4 strain, of Actinomycetes. Benanomicins A and B each show antifungal activity and are useful as a therapeutic antifungal agent. A new compound, dexylosylbenanomicin B is now produced by chemical conversion of benanomicin B, and this semi- synthetic antibiotic also shows antifungal activity and is useful as a therapeutic antifungal agent.

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