Fibrinolytic enzyme derivatives

C - Chemistry – Metallurgy – 12 – N

Patent

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195/35.3, 167/10

C12N 9/50 (2006.01) C07D 213/71 (2006.01) C12N 11/06 (2006.01)

Patent

CA 1271718

Abstract A derivative of a fibrinolytic enzyme in which the catalytic site on the enzyme which is responsible for fibrinolytic activity is blocked by a human protein attached thereto by way of a reversible linking group. Such derivatives are useful for treating thrombotic diseases in humans.

470956

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