Structures for controlled chemical release

Details Structures for controlled chemical release Structures for controlled chemical release

A - Human Necessities

61

K

167/153, 167/159

A61K 9/24 (2006.01) A61K 9/00 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01) G03F 7/00 (2006.01) G03F 7/26 (2006.01)

Patent

CA 1280073

ABSTRACT STRUCTURES FOR CONTROLLED CHEMICAL RELEASE A method of fabricating a structure for the controlled release of a substance located in the structure between two relatively insoluble layers in which a first relatively insoluble layer (9), a soluble layer containing the substance to be released (12a,b) and a second relatively insoluble layer (15) are deposited sequentially on a substrate (8), followed by the removal of the substrate, the shapes of the layers being such that the soluble layer is entirely surrounded by the relatively insoluble layers except for one or more release orifices. The shape of the soluble layer may be designed to provide a pulsed release of the substance or may comprise a plurality of different substances to be released. The structure may conveniently be fabricated by layer processing including photolithography and etching on a soluble layer of silicon dioxide formed on a piece of silicon.

519505

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