Imidazodiazepine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/14 (2006.01) A61K 31/55 (2006.01) C07D 495/22 (2006.01)

Patent

CA 1259612

RAN 4008/337 Abstract The novel imidazodiazepine derivatives of the formula Image I wherein A together with the carbon atoms denoted by .alpha. and .beta. signifies the group Image or Image (a) (b) one of R1 and R2 signifies hydrogen and the other signifies hydrogen. halogen or trifluoromethyl, R3 and R4 each signify hydrogen or halogen and n signifies the number 2 or 3, the compounds having the (S)- or (R,S)-configuration with reference to the carbon atom denoted by .gamma.. and their pharmaceutically acceptable acid addition salts have anxiolytic, anticonvulsant, muscle relaxant and sedative-hypnotic properties. They can be manufactured in a manner known per se and can be processed to provide galenical administration forms.

500747

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