Amino acid derivative anticonvulsant

Details Amino acid derivative anticonvulsant Amino acid derivative anticonvulsant

C - Chemistry, Metallurgy

07

C

167/269, 530/5.0

C07C 237/22 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/195 (2006.01) A61K 38/00 (2006.01) C07C 237/00 (2006.01) C07C 323/59 (2006.01)

Patent

CA 1340902

Compounds useful in the treatment of epilepsy and other central nervous system disorders of the general formula: (see above formula) wherein R and R1, independently, are lower alkyl, aryl lower alkyl or phenyl, unsubstituted or substituted with at least one electron withdrawing substituent or at least one electron donating substituent; R2 and R3, independently, are hydrogen, lower alkyl, aryl lower alkyl or phenyl, unsubstituted or substituted with at least one electron withdrawing substituent or at least one electron donating substituent; n is 1 to 4; and the pharmaceutically acceptable salts thereof.

501869

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