N-substituted alkylidene-1,2,3,4-tetrahydro-9-...

Details N-substituted alkylidene-1,2,3,4-tetrahydro-9-... N-substituted alkylidene-1,2,3,4-tetrahydro-9-...

C - Chemistry, Metallurgy

07

D

167/226, 260/277

C07D 219/10 (2006.01) C07D 221/16 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 1334669

There are disclosed compounds having the formula Image wherein n is 1-4; R1 is hydrogen, alkyl, aryl, arylloweralkyl, naphthyl, furyl, thienyl, pyridinyl or pyrrolyl; X is hydrogen, loweralkyl, cycloalkyl, loweralkoxy, halogen, hydroxy, nitro, trifluoromethyl, formyl, loweralkylcarbonyl, arylcarbonyl, -SH, loweralkylthio, -NHCOR2 or -NR3R4 where R2 is hydrogen or loweralkyl, and R3 and R4 are independently hydrogen, loweralkyl or cycloalkyl; stereo, optical and geometrical isomers thereof, and pharmaceutically acceptable acid addition salts thereof, which are useful for enhancing memory and pharmaceutical compositions comprising an effective memory enhancing amount of such a compound.

576693

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