Hydroxymethyl cyclobutyl purines

C - Chemistry – Metallurgy – 07 – D

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C07D 239/48 (2006.01) A61K 31/505 (2006.01) C07C 31/44 (2006.01) C07C 35/04 (2006.01) C07C 309/66 (2006.01) C07C 309/73 (2006.01) C07D 239/46 (2006.01) C07D 239/54 (2006.01) C07D 473/00 (2006.01)

Patent

CA 1340496

Antiviral activity is exhibited by compounds having the formula (see fig. I) and their pharmaceutically acceptable salts. R1 is (see fig. II), (see fig. III), (see fig. IV), (see fig. V), (see fig. VI), (see fig. VII), (see fig. VIII), (see fig. IIX), (see fig. IX), (see fig. X), (see fig. XI) R2 is hydrogen, -PO3H2, wherein R3 is hydrogen, alkyl, substituted alkyl, or aryl, and R4 is alkyl.

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