C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/47
C12N 5/04 (2006.01) C12N 5/00 (2006.01) C12P 17/18 (2006.01)
Patent
CA 1283874
ABSTRACT OF THE DISCLOSURE Synthesis of alkaloids by suspension cultured Catharanthus roseus cells is enhanced by stressing the cultured cells osmotically by addition to the culture of such inducers as ionic osmotic stressors such as halide salts e.g. NaCl, KCl and FeCl3 or organic osmotic stressors such as sugar alcohols and sugar acids. Synthesis of alkaloids is also enhanced by addition of anti-gibberellin compounds and other compounds such as abscisic acid which is a plant growth regulator. Yields of alkaloids are consequently increased.
543676
Misawa Masanaru
Smart Nigel John
Smith Jane Isobel
Allelix Biopharmaceuticals Inc.
Mccarthy Tetrault Llp
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