Aglycons of a/16686 antibiotics

Details Aglycons of a/16686 antibiotics Aglycons of a/16686 antibiotics

C - Chemistry, Metallurgy

07

K

530/11.02, 167/1

C07K 11/02 (2006.01) A61K 38/15 (2006.01) C07K 11/00 (2006.01)

Patent

CA 1337838

The invention concerns the aglycons of factors A1, A2, A3, A'1, A'2, A'3 of antibiotic A/16686, their respective tetra- hydroderivatives and mixtures thereof. The aglycons are produced by selective hydrolysis of the above mentioned factors. The compounds have antibacterial activity, in particular, against widely diffused gram positive bacteria and are particularly useful for topical treatment of wound infections and acne.

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