Human protein s, a plasma protein regulator of hemostasis

Details Human protein s, a plasma protein regulator of hemostasis Human protein s, a plasma protein regulator of hemostasis

C - Chemistry, Metallurgy

12

N

195/1.22, 195/1.

C12N 15/12 (2006.01) C07K 14/745 (2006.01) C12N 1/21 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1338260

The present invention comprises novel DNA compounds which encode human protein S activity. The human protein S cDNA sequence consists of a coding region for a 676 amino acid precursor; the coding region encodes a 41 amino acid leader peptide, 635 amino acids corresponding to the mature protein, and a stop codon. Eukaryotic expression vectors have been constructed which comprise the novel protein S activity-encoding DNA and drive expression of protein S when transformed into an appropriate host cell.

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