Luzopeptin e.sub.2

C - Chemistry – Metallurgy – 07 – G

Patent

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195/89, 530/7.06

C07G 11/00 (2006.01) C07K 7/06 (2006.01) C12P 21/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1220746

ABSTRACT A novel cyclic depsipeptide antibiotic named luzopeptin E2 is produced by fermentation of Actinomadura luzonensis ATCC 31491 and isolation of the antibiotic free of substances co-produced therewith. Luzopeptin E2 exhibits antimicrobial activity and inhibits the growth of mammalian tumors.

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