Process for the preparation of a biologically active extract

A - Human Necessities – 61 – K

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A61K 35/12 (2006.01) A61K 35/14 (2006.01) A61K 35/26 (2006.01) A61K 35/28 (2006.01) A61K 35/34 (2006.01) A61K 35/407 (2006.01) A61K 35/50 (2006.01)

Patent

CA 1230553

Abstract A mammal organ, for example the thymus, or a cell culture is comminuted to form a slurry, accompanied by cell disintegration, high molecular weight substances are precipitated by heating and removed by centrifuging, and residual substances of molecular weight greater than 10,000 are separated out by ultrafiltration; finally, the salts are substantially removed by electrodialysis. A biologically active, low-salt, sterile, pyrogen-free and antigen-free complete extract is obtained and, in con- trast to all known processes, no foreign substance or auxiliary, other than water - not even a preservative or a carrier for separation methods - is used.

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