Substituted 5-phenyl-2- (1h)-pyridimidinone compounds

Details Substituted 5-phenyl-2- (1h)-pyridimidinone compounds Substituted 5-phenyl-2- (1h)-pyridimidinone compounds

Category

C - Chemistry, Metallurgy

Subcategory

07

Subsubcategory

D

CPC

167/218, 260/255

IPC codes

C07D 239/36 (2006.01) A61K 31/505 (2006.01)

Type

Patent

Patent number

CA 1248103

Description

Abstract New substituted phenyl-2-(1H)-pyrimidinones of the general formula I Image (I) in which R1 denotes an alkyl group having 1 to 4 carbon atoms, and R2 and R3, which can be identical or different, each denote hydrogen, halogen, cyano, a trifluoromethyl group, a hydroxyl group or an alkoxy group having 1 to 4 carbon atoms, it being possible for each alkyl moiety to be straight-chain or branched, and their tautomeric forms and their acid addition salts and N-oxides have a positive inotropic effect and can thus be used as medicaments for the treatment of cardiac insufficiency.

Application Number

452942

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