Pyridazinone derivatives

Details Pyridazinone derivatives Pyridazinone derivatives

C - Chemistry, Metallurgy

07

D

260/264.1

C07D 237/02 (2006.01) C07D 237/04 (2006.01) C07D 237/14 (2006.01) C07D 237/36 (2006.01) C07D 491/04 (2006.01) C07D 491/052 (2006.01)

Patent

CA 1320957

ABSTRACT The present invention relates to a compound having the formula below which have an excellent cardiotonic action: Image wherein Y represents C1-4 alkylene which may be substituted by C1-18 alkyl, C1-5 alkoxy C1-5 alkylthio C1-5 alkyl, C1-5 alkoxycarbonyl or benzyl, or Image (where each r1 and r2 represents hydrogen, C1-18 alkyl, C1-5 alkoxy, C1-5 alkylthio C1-5 alkyl, C1-5 alkoxycarbonyl or benzyl); and R1 represents hydrogen, C1-5 alkyl which may be substituted by C1-5 alkoxy, acetyl or C2-5 alkenyl; and R2 represents hydrogen or methyl; and each R3 and R4 represents hydrogen, halogen, hydroxy, C1-5 alkyl, or C1-5 alkoxy; and R5 represents hydrogen or C1-5 alkyl which may be sustituted by hydroxy; and R1 and R5 may form ring by joining each other; and ? represents single or double bond.

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