Chromone-and thiochromone-substituted 1,4-dihydro-...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/048 (2006.01) C07D 307/66 (2006.01) C07D 491/04 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1211109

ABSTRACT Dihydrbpyridines of the formula Image in which R1, R2, R5 and R6 can be hydrogen or various halogen or organic radicals, R4 is an optionally substituted hydrocarbon radical, A is a direct bond, a C1-C20-alkylene chain or a C2-C20-alkenylene chain, which chains are optionally interrupted by O or S X is O or S, and Y is a direct bond, O, S, -NH- or -N-aklyl with 1 to 8 C atoms or a pharmaceutically acceptable salt, are useful as cardiotonic agents for improving heart contrac- tility, antihypotonic agents, for lowering the blood sugar level, for detumescing mucous membranes and for influenc- ing the salt and/or liquid balance.

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