Process for differentiating the origin of particles in urine

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G01N 33/536 (2006.01) G01N 33/68 (2006.01)

Patent

CA 1235656

Abstract A Process For Differentiating The Origin Of Particles In Urine Urinary particulates in a human subject which have been coated with THP is determined to be from the region of the nephron which is above the Henle loop in the nephron where THP is produced. The identification of those particles in the urine sample which had been coated with THP is performed by subjecting the sample to THP antibodies to form THP antibody-antigen com- plexes. These complexes can be identified by a number of ways, such as visual, fluorescent, etc. By deter- mining the percentage of the total particulates which have the coating of THP, a diagnostic tool for determining renal disorders is disclosed.

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