Fodder additive and a process for the preparation thereof

A - Human Necessities – 23 – K

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99/30, 99/24.3

A23K 1/16 (2006.01) A61K 31/50 (2006.01)

Patent

CA 1295174

ABSTRACT OF THE DISCLOSURE The invention relates to fodder additives comprising a compound inducing the microsomal enzyme system of the liver of the formula (I) Image (?) wherein R1, R2 and R3 are identical or different and stand for hydrogen, halogen, trihalomethyl, or alkyl or alkoxy each containing from 1 to 6 carbon atoms; R4 is phenyl, dialkylaminocarbonyl or alkoxy-carbonyl having from 1 to 6 carbon atoms in the alkyl and alkoxy moieties, respectively; R5 is hydrogen or methyl, or together with R4 and the adjacent nitrogen atom forms a hetero-ring having up to 8 members; n is 1, 2, 3, 4 ot 5; m is 0 or 1, a is 0 or 1, with the proviso that if a = O, R1 is trihalomethyl and R2 and R3 both are hydrogen, preferably in amount of 0.5 to 99 % by weight, in admixture with conventional carriers and/or additives and optionally at least one further active ingredient conventionally used in the animal husbandry. The enzyme inducing compounds used according to the invention accelerate the elimination of various xenobiotics metabolizing in the liver.

493814

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