Imidazodiazepines

Details Imidazodiazepines Imidazodiazepines

C - Chemistry, Metallurgy

07

D

260/239.4

C07D 471/22 (2006.01) C07D 209/38 (2006.01) C07D 265/26 (2006.01) C07D 471/14 (2006.01) C07D 487/04 (2006.01) C07D 487/14 (2006.01) C07D 495/04 (2006.01) C07D 495/14 (2006.01) C07D 495/22 (2006.01)

Patent

CA 1185602

ABSTRACT There are described novel pharmaceutically active substances with valuable pharmacodynamic properties which exhibit especially pronounced anticonvulsive and anxiolytic activities and have only a low toxicity. These active substances correspond to the general formula Image I wherein A together with the two carbon atoms denoted as .alpha. and .beta. signifies the group Image (a) , (b) , (c) or (d) B signifies dimethylene, trimethylene or propenylene, R1 signifies hydrogen, halogen, trifluoromethyl, amino, nitro, cyano or lower alkyl and R2 signifies hydrogen, halogen, trifluoromethyl, amino, nitro, cyano, lower alkyl, lower alkoxy, lower alkylthio, lower alkyl- sulphinyl or lower alkylsulphonyl, and the carbon atom denoted as .gamma. has the (S)- or (R,S)-configuration, and can be used as medicaments in the form of pharmaceutical preparations.

394685

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