Protein label and drug delivery system

Details Protein label and drug delivery system Protein label and drug delivery system

C - Chemistry, Metallurgy

07

D

167/129, 167/139

C07D 311/82 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 1/107 (2006.01) G01N 33/532 (2006.01) G01N 33/533 (2006.01)

Patent

CA 1330145

PROTEIN LABEL AND DRUG DELIVERY SYSTEM ABSTRACT OF THE DISCLOSURE A bridging molecule carrying a drug, or a label such as a fluorophore, which adds across disulfide bonds of molecules, particularly proteins, and methods of manufacturing and using the bridging molecules, are disclosed. The bridging molecule is reactive with sulfhydryl groups formed by the reduction of disulfide bonds of the protein. The functional groups of the bridging molecules are typically -SH groups.

522594

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