Fluoromethylthiooxacephalosporins

Details Fluoromethylthiooxacephalosporins Fluoromethylthiooxacephalosporins

C - Chemistry, Metallurgy

07

D

260/244.2

C07D 498/04 (2006.01) C07D 505/00 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1236099

- Abstract - An antibacterial 7.beta.-(fluorinated methylthioacetamido)- 7.alpha.-methoxy-3-(1-hydroxyalkyl-5-tetrazolyl)thiomethyl-1-dethia- 1-oxa-3-cephem-4-carboxylic acid and its derivatives at the carboxy or hydroxyalkyl represented by the following formula: Image wherein, R is FCH2- or F2CH-; R1 is R3O-substituted-alkyl in which R3 is hydrogen or a hydroxy-protecting group; and R2 is a hydrogen or light metal atom or a carboxy-protecting group, antibacterial drugs containing it, its use and production. - 1 -

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