Retinoic esters of macrolids, process for their preparation,...

Details Retinoic esters of macrolids, process for their preparation,... Retinoic esters of macrolids, process for their preparation,...

C - Chemistry, Metallurgy

07

H

167/185, 260/230

C07H 15/16 (2006.01) A61K 8/67 (2006.01) C07H 17/08 (2006.01)

Patent

CA 1313662

PRECIS DE LA DIVULGATION L'invention concerne des esters d'acide rétinoîques all trans et 13-cis de macrolides répondant à la formule suivante: Image (I) dans laquelle R représente un radical dérivé d'un macrolide à l'exclusion de l'érythromycine A, et les mélanges et sels desdits esters. L'invention concerne également leur procédé de préparation et des compositions pharmaceutiques et cosmétiques les contenant. Ces esters et compositions les contenant sont utiles dans le traitement de diverses dermatoses.

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