Synthesis of acylated benzothiophenes

C - Chemistry – Metallurgy – 07 – D

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260/279.25, 260/

C07D 409/12 (2006.01) C07D 295/04 (2006.01) C07D 333/56 (2006.01)

Patent

CA 1167036

ABSTRACT OF THE DISCLOSURE A qroup of 6-hydroxy-2-(4-hydroxyphenyl)-3- [4-[2-aminoethoxy)benzoyl]benzo[b]thiophenes are pre- pared by acylation of a methyl-protected starting com- pound followed by demethylation in a single reaction mixture.

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