Thiochroman esters of phenols and terephthallates having...

C - Chemistry – Metallurgy – 07 – D

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167/242, 260/328

C07D 335/06 (2006.01) A61K 31/38 (2006.01)

Patent

CA 1334424

Compounds of formula I Image in which: the R groups are independently hydrogen or lower alkyl, one of the R groups being attached to the thiochroman ring at the 6 or the 7 position; one of A and B is O or S and the other is -C(O)-,A being attached to the thiochroman ring at the 6 or 7-position, with one of the R groups being attached to the other of said 6 and 7 position; n is 0-5; and Z is H, an acid or acid derivative, an alcohol or alcohol derivative, acetal or acetal derivative or ketone or ketone derivative, or a pharmaceutically acceptable salt, have retinoid-like activity.

604151

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