Class of acyl-derivatives of carnitine, process for...

C - Chemistry – Metallurgy – 07 – D

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C07D 333/24 (2006.01) A61K 31/14 (2006.01) A61K 31/195 (2006.01) A61K 31/205 (2006.01) A61K 31/215 (2006.01) A61K 31/38 (2006.01) C07D 333/22 (2006.01) C07D 333/32 (2006.01) C07D 333/38 (2006.01) C07D 339/02 (2006.01) C07D 339/04 (2006.01)

Patent

CA 1178971

"Novel class of acyl-derivative5 of carnitine, process for preparing same and therapeutic use thereof". ABSTRACT OF THE DISCLOSURES A novel class of acyl-derivatives of carnitine is disclosed wherein the acyl radical is either tne radical of unsaturated organic acids (typically, acrylic acid) or the radical of saturated organic acids substituted with tert- -alkyl, cycloalkyl, cycloalkenyl, alkoxyl, heterocyclic and carboalkoxylradicals, or with aldehyde or hydroxy groups. These acyl-derivatives of carnitine are useful therapeutical agents in the treatment of cardiac disorders, hyperlipidaemias and hyperlipoproteinaemias.

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