Method for controlling hemophilia in mammals

A - Human Necessities – 61 – K

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167/103.34

A61K 35/14 (2006.01) A61K 9/127 (2006.01) A61K 38/48 (2006.01)

Patent

CA 1223204

ABSTRACT OF THE DISCLOSURE A method for controlling HemophiliaA(Antihemophilic Factor (F. VIII:C) deficiency) in mammals is described. Factor VIII:C deficiency in the mammal is bypassed by infusion of a synergistic mixture of a phospholipid and Factor Xa so that the cascade process of blood clotting may continue. The proportions of phospholipid and Factor Xa in the mixture are critical as too little Xa has no effect while too much is toxic (thrombogenic).

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