Combination therapy using interleukin-2 and/or...

Details Combination therapy using interleukin-2 and/or... Combination therapy using interleukin-2 and/or...

A - Human Necessities

61

K

167/103.1, 167/1

A61K 31/48 (2006.01) A61K 38/20 (2006.01) A61K 38/21 (2006.01)

Patent

CA 1290249

Abstract of the Disclosure Anti-tumor activity in mammals can be augmented by administering to the mammalian host a synergistically effective amount of TNF and IL-2 or of TNF and IFN-.beta., or of TNF, IL-2 and IFN-.beta. in combination. The composition of TNF and IL-2 and/or IFN-.beta. may be prepared in vitro or administered separately to the host. If the TNF and IL-2 are administered sequentially, the TNF must be administered prior to the IL-2 to obtain synergy. The composition is useful for treating such cancers as mastocytoma, melanoma, leukemia, and lymphoma.

531901

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