Method and cell line for obtaining plasminogen activators

C - Chemistry – Metallurgy – 12 – N

Patent

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195/43

C12N 5/06 (2006.01)

Patent

CA 1291055

ABSTRACT A chemically defined growth medium designated as SYC medium, containing for example fetuin, bovine serum albumin, insulin, transferrin, 5.alpha.- dihydrotestosterone and dexamethasone, is suitable for adapting a plasminogen activator-secreting cell line to growth in the absence of fetal calf serum. Such cell lines are capable of producing relatively large quantities of plasminogen activator.

615619

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