Process for preparing 7-hydroxyindole derivatives and the...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/10 (2006.01) A61K 31/465 (2006.01) C07D 211/26 (2006.01) C07D 401/04 (2006.01)

Patent

CA 1266663

PRECIS DE LA DIVULGATION: L'invention concerne un procédé pour préparer des nouveaux dérivés du 7-hydroxy indole et leurs sels avec les acides minéraux ou organiques, de formule générale (I): Image (I) dans R = H, alkyle C1-C5, alkyle insaturé C3-C7, cycloalkyl- alkyle C4-C7, aralkyle C7-C12 éventuellement substitué, R1 = OH, alkoxy C1phénylalkyloxy C7-C9, phénoxy. Les dérivés obtenus par ce procédé présentent de remarquables propriétés dopaminergiques et peuvent être utilisés comme médicaments.

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