Method and apparatus for linearizing rate assays

Details Method and apparatus for linearizing rate assays Method and apparatus for linearizing rate assays

G - Physics

01

N

354/30

G01N 21/00 (2006.01) C12Q 1/00 (2006.01) G01N 33/50 (2006.01)

Patent

CA 1179777

-0- METHOD AND APPARATUS FOR LINEARIZING RATE ASSAYS Abstract A method and apparatus are described for the determination of rate reactions in a test liquid, where- in a detectable signal representative of the current status of the reaction is measured over plural times and the rate of change in the signal is ascertained. The method and apparatus provide for the step of determining a value representing the signal produced by a reference liquid having a predetermined analyte concentration or activity, at the same plural times as are used to evaluate the test liquid, and using the value rep- resenting the reference signal at each of the plural times to arithmetically operate on the corresponding value obtained for the test liquid. It has been found that the arithmetic operation step acts to make the rate reaction more readily determinable.

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