C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/292
C07D 211/14 (2006.01) C07D 295/08 (2006.01) C07D 295/092 (2006.01)
Patent
CA 1216293
Abstract The invention relates to new piperidine derivatives of the formula (I) Image (1) wherein R1 is halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms; and R2 is alkyl having from one to 4 carbon atoms, and acid addition and quaternary ammonium salts thereof. According to another aspect of the invention there are provided processes for the preparation of these compounds. The compounds of the formula (I) are pharmacologically active. In particular, they inhibit the microsomal monooxigenase enzyme system of the liver. Pharmaceutical compositions containing them as active ingredient are also within the scope of the invention.
444205
Gorog Sandor
Hajdu Istvan
Palosi Eva
Szeberenyi Szabolcs
Szporny Laszlo
Fetherstonhaugh & Co.
Richter Gedeon Vegyeszeti Gyar Rt
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