Preparation of 2-t-butyl-5-chloropyrimidine

Details Preparation of 2-t-butyl-5-chloropyrimidine Preparation of 2-t-butyl-5-chloropyrimidine

C - Chemistry, Metallurgy

07

D

260/251

C07D 239/30 (2006.01)

Patent

CA 1215059

ABSTRACT OF THE DISCLOSURE 2-t-Butyl-5-chloropyrimidine is made by the direct chlorination of 2-t-butylpyrimidine with ele- mental chlorine in an acetic or propionic acid solution at temperatures of 40° to 90°C in the presence of a buffer.

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