Spiro-tricyclicaromatic succinimide derivatives as...

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C - Chemistry, Metallurgy

07

D

260/250, 260/299

C07D 209/96 (2006.01) C07C 45/46 (2006.01) C07C 45/65 (2006.01) C07D 221/16 (2006.01) C07D 235/02 (2006.01) C07D 263/52 (2006.01) C07D 277/60 (2006.01) C07D 295/073 (2006.01) C07D 333/24 (2006.01) C07D 333/28 (2006.01) C07D 333/78 (2006.01) C07D 471/10 (2006.01) C07D 487/20 (2006.01) C07D 491/10 (2006.01) C07D 495/10 (2006.01) C07D 495/22 (2006.01) C07D 498/10 (2006.01) C07D 513/10 (2006.01) C07D 513/20 (2006.01) C09D 127/06 (2006.01)

Patent

CA 1269661

Abstract Disclosed are substituted or unsubstituted planar tricyclic fluorene or nuclear analogs thereof, spiro-coupled to a five-membered ring containing a secondary amide, and the pharmaceutically acceptable salts thereof. These compounds are useful, inter alia, in the treatment of diabetes. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when indicated for, inter alia, long term, prophylactic treatment of the diabetes syndrome.

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