Oximes of 3'"-dehydrocardenolide tridigitoxosides

Details Oximes of 3'"-dehydrocardenolide tridigitoxosides Oximes of 3'"-dehydrocardenolide tridigitoxosides

C - Chemistry, Metallurgy

07

J

260/8

C07J 41/00 (2006.01)

Patent

CA 1205072

ABSTRACT Oximes of 3'"-dehydrocardenolide tridigitoxosides The present invention provides 3'"-dehydro- cardenolide tridigitoxoside oximes of the general formula:- Image (I) in which R1 is a hydrogen atom or an alkyl radical containing up to 3 carbon atoms, R2 is a hydrogen atom or a lower acyl or alkyl radical and R3 OH represents two hydrogen atoms, the group Image or the oximino group =NOR1, wherein R1 has the above- given meaning. The present invention also provides a process for the preparation of these oximes, as well as pharmaceutical compositions containing them which are useful for the treatment of cardiac insufficiency.

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