C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/557, 260/604
C07C 47/277 (2006.01) C07C 45/30 (2006.01) C07C 205/32 (2006.01) C07C 205/33 (2006.01) C07C 205/35 (2006.01)
Patent
CA 1188324
Abstract New substituted phenoxyalkanolamines and pheroxy- alkanol-cycloalkylamines of the general formula I Image (I) in which R1 and R2, which can be identical or different, denote alkyl groups with in each case 1 to 4 carbon atoms, or R1 and R2 together denote the group -(CH2)n-, wherein n is the number 4 or 5, R3 denotes hydrogen, or an alkyl group or an acyl group with in each case 1 to 6 carbon atoms, R4 denotes an alkyl group with 1 to 4 carbon atoms or the cyclopropylmethyl group and R5 denotes hydrogen halogen or alkyl, and acid addition salts thereof, have a cardioselective .beta.1-adrenolytic and hypotensive action. They can be used as medicaments for the treat- ment of angina pectoris, hypertension and arrhythmias.
418219
Beiersdorf Aktiengesellschaft
Gowling Lafleur Henderson Llp
LandOfFree
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