Dihydropyridine combination product

Details Dihydropyridine combination product Dihydropyridine combination product

A - Human Necessities

61

K

167/229

A61K 31/44 (2006.01)

Patent

CA 1261272

ABSTRACT A solid medicament formulation which can be admini- stered orally, comprising l to 40 mg of a dihydropyridine of the formula. Image in which Rl and R3 are always different from one another and represent alkyl which has l to 12 carbon atoms and which is optionally sub- stituted once or several times by fluorine or chlorine or which is optionally interrupted by an oxygen atom in the chain, and represents the radical Image R2 representing one or two substituents from the group con- sisting of nitro, chlorine and trifluoromethyl, or represents Image and 0.1 to 100 mg of a cardioactive nitrate. The composition is cardioactive and the patientls tendency toward nitrate tolerance is reduced.

512761

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