Pharmaceutical preparations

Details Pharmaceutical preparations Pharmaceutical preparations

A - Human Necessities

61

K

167/163

A61K 9/10 (2006.01) A61K 9/107 (2006.01) A61K 47/00 (2006.01) A61K 47/18 (2006.01) C07D 213/20 (2006.01) C07D 213/30 (2006.01) C07D 213/63 (2006.01) C07D 213/65 (2006.01) C07D 213/68 (2006.01) C07D 213/69 (2006.01) C07D 213/73 (2006.01) C07D 213/80 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 233/54 (2006.01) C07D 235/06 (2006.01) C07D 239/26 (2006.01) C07D 239/30 (2006.01) C07D 239/36 (2006.01) C07D 239/46 (2006.01) C07D 239/47 (2006.01) C07D 239/54 (2006.01) C07D 239/553 (2006.01) C07D 241/2

Patent

CA 1319321

Abstract A pharmaceutical preparation is disclosed which is made up of a micelle or a vesicle each consisting of a cationic tenside with a monovalent ion and a hydrophobic cyclic or linear peptide, dispersed in a solvent whose pH value lies between pH 7 - pH 8, the critical micellization concentration (cmc) lying in the range of 1.0 . 10-7 to 7.0 . 10-5 mol/litre. The preparations disclosed have in particular the advantage that by the increasing of the hydrophobicity of the alkyl or aryl chain or the radical at the N+ tenside both the mem- brane permeability is increased and furthermore the pharma- ceutical active substance, in particular linear and cyclic tyrocidines (A - E), can be transferred actively into the cytosol. They thus act on the transcription level. In addition, linear and cyclic tyrocidines in particular have antiviral effects.

543931

Affiliated with

Also associated with

Rating

Pharmaceutical preparations does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical preparations, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical preparations will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1313089