Bis-esters of methanediol with penicillins and penicillanic...

C - Chemistry – Metallurgy – 07 – D

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C07D 499/44 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1200545

BIS-ESTERS OF METHANEDIOL WITH PENICILLINS AND PENICILLANIC ACID 1,1-DIOXIDE Abstract 6'-Acylaminopenicillanoyloxymethyl esters of peni- cillanic acid 1,1-dioxide are useful as antibacterial agents. The 6'-aminopenicillanoyloxymethyl ester, halomethyl esters, alkylsulfonyloxymethyl esters and arylsulfonyloxymethyl esters of penicillanic acid 1,1- dioxide are all useful intermediates for the aforesaid antibacterial agents.

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