C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/179, 260/292
C07D 211/22 (2006.01) A01N 33/08 (2006.01) A01N 43/40 (2006.01) A61K 31/445 (2006.01) C07D 211/14 (2006.01) C07D 217/04 (2006.01) C07D 295/08 (2006.01) C07D 295/084 (2006.01)
Patent
CA 1312079
ABSTRACT OF THE DISCLOSURE The present invention relates to new aromatic derivatives of formula: Image (I) wherein: - Alk is an alkylene group with 2 to 10 carbon atoms, - R1 is hydrogen or an alkyl with 1 to 6 carbon atoms, - R2 and R3 are similar or different and represent a cycloalkyl with 3 to 6 carbon atoms or a straight or branched alkyl with 1 to 6 carbon atoms, either substi- tuted or non-substituted by a phenyl or methyl phenyl group, or R2 and R3 form, together with the atom of nitrogen to which they are bonded, a mono-nitrogenous heterocycle containing no other heteroatom, such as pyrrolidino, piperidino, azepino, hexamethylene-imino, 4-methyl-piperidino, 4-phenyl-piperidino, 1,2,3,4- tetrahydro-2-isoquinolyl, 4-benzyl-piperidino; - R4 is hydrogen, halogen, methyl or phenyl, - R5 is hydrogen, halogen or methyl, - or R4 and R5 together with the benzene ring to which they are bonded, constitute a 1-naphthyl or 2-naphthyl group, and their salts with mineral or organic acids. The invention compounds possess interesting antimicrobial properties.
520312
Demarne Henri
Mosse Madeleine
Proietto Vincenzo
Demarne Henri
Mosse Madeleine
Proietto Vincenzo
Sim & Mcburney
Societe Anonyme: Sanofi
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